Evolution of Germline Cancer Genomics from Rare Disorders to Precision Oncology Trials – Sharon Plon

Sharon Plon, M.D., Ph.D., is a medical geneticist with a longstanding focus on cancer genetics and clinical genomics, using translational research on mechanisms of pediatric cancer through large collaborative projects. She worked on a landmark study of the association of birth defects and childhood cancer and is using whole genome sequencing of these unique patients to identify novel cancer susceptibility genes. Dr. Plon has served on the National Advisory Council for Human Genome Research and the Board of Directors of the American Society of Human Genetics. Since 2013, Dr. Plon has served as a PI of the Clinical Genome (ClinGen) Resource and chairs the ClinGen hereditary cancer group. She also co-chairs the germline reporting effort of the national NCI/COG Pediatric MATCH Precision Oncology trial.

The National Human Genome Research Institute (NHGRI) established The Jeffrey M. Trent Lectureship in Cancer Research in 2003 in honor of its founding scientific director, who served in this role for more than nine years. His leadership and vision were instrumental in establishing NHGRI's Division of Intramural Research as one of the premier research programs in the world devoted to genetics and genomics. The annual Trent Lecture is given by a prominent cancer researcher who brings the kind of energy, creativity and enthusiasm to cancer research that Dr. Trent has exemplified throughout his career.

Learn more about the Jeffrey M. Trent Lectureship in Cancer Research: https://www.genome.gov/event-calendar/Jeffrey-Trent-Lectureship-in-Cancer-Research