Estrogen and Heart Health - What's the Connection?

Learn about the connection between Estrogen and Heart Health in this informative interview. In this video, we hear from Dr. Glen Pyle PhD, a Professor of Molecular Cardiology and Senior Researcher in Women's Heart Health. From the function of estrogen in the body to the impact of menopause on heart disease, this interview provides a comprehensive overview of how the heart changes with age, and what women can do to lower their risk of cardiovascular disease.

Whether you're a woman looking to better understand how to protect your heart health as you age, or simply want to learn more, this interview is a valuable resource. Please share this interview with the women in your life!

CHAPTERS:
00:00 Dr. Pyle's journey to women's heart health research
07:35 Common Misconceptions about Heart Disease in women
10:03 Genetics and other Risk Factors for Cardiovascular Disease in Women
13:23: Hormonal Changes in Women that are associated with increased Cardiovascular Risk
17:42 How does the age of Menopause onset increase risk for Heart Disease?
19:36 How changes in Adipose tissue affect the Heart
23:08 How Blood Vessels changes after Menopause
24:55 Immune Function after Menopause
25:53 Hormone Replacement Therapy and Menopause
32:21 Timing of Hormone Replacement Therapy
34:02 Changes in the Post-menopausal heart: Estrogen, Stress, and Inflammation
36:36 Why women with heart disease are more likely to be misdiagnosed than men
36:42 Women are less likely to be triaged correctly when suffering a heart attack
40:00 Cardio-protective treatment based on the sex of the individual
42:35 Heart Disease Advocacy and Education for patients and healthcare professionals
48:12 Recognizing a woman’s risk for Cardiovascular Disease
49:02 Mental Health and Heart Health

Resources:
Protecting heart health after menopause: https://www.heartandstroke.ca/articles/protecting-heart-health-after-menopause

Ground-breaking research into the impact of menopause on the heart: https://impart.team/ground-breaking-research-into-the-impact-of-menopause-on-the-heart/

Cardiovascular health after menopause transition, pregnancy disorders, and other gynaecologic conditions: a consensus document from European cardiologists, gynaecologists, and endocrinologists: https://pubmed.ncbi.nlm.nih.gov/33495787/

Sex differences in heart failure with preserved ejection fraction: From traditional risk factors to sex-specific risk factors: https://pubmed.ncbi.nlm.nih.gov/36448661/

Cardiac changes during the peri-menopausal period in a VCD-induced murine model of ovarian failure: https://pubmed.ncbi.nlm.nih.gov/31050200/

American Heart Association: https://www.heart.org

Canadian Heart Research Centre (CHRC): https://www.chrc.net

About Our Guest Expert:
Dr. Glen Pyle is a member of IMPART at Dalhousie Medicine and a Professor of Molecular Cardiology at the University of Guelph. He was named a Senior Career Investigator for Women's Heart Health by the Heart and Stroke Foundation of Canada for his work on the role of menopause in shaping cardiovascular disease risk. The Pyle lab has also worked to develop peptide therapeutics for heart attacks based on studies investigating cardiac Z-disc proteins.

Dr Pyle earned his PhD in Physiology and Biophysics at the University of Tennessee Health Sciences Center and was an American Heart Association Post-Doctoral Fellow at the University of Illinois Medical Center in Chicago. His lab is supported by the Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, and the Natural Sciences and Engineering Research Council of Canada.

About Lindsay:
Lindsay Dixon is a Pharmacist from British Columbia, Canada. She obtained her Bachelor of Science degree in Brazil where she specialized in Pharmacotherapy. Lindsay is also certified in Palliative Care through the University of Victoria. Lindsay has over 10 years of experience working in community pharmacy and in community pharmacy management. Her passion lies in preventative medicine, patient-centred care, and public health education.

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#podcast #womenshealthtalk #perimenopause #menopause #heartdiseaseawereness #hormonereplacementtherapy