Dr. Sara Gottfried: How to Optimize Female Hormone Health for Vitality & Longevity | Huberman Lab

My guest is Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and clinical assistant professor of integrative medicine & nutritional sciences at Thomas Jefferson University. Dr. Gottfried specializes in hormone health, vitality and longevity using precision/personalized approaches. We discuss female hormone health, puberty, perimenopause, and menopause, hormone testing, the microbiome, stress related hormone challenges, their causes, and various treatments. We also discuss fertility, birth control and tools for improving microbiome health, treating PCOS, insulin management, and the best nutrition, supplementation, and exercise programs for women. While the episode focuses mainly on female hormones, males will also benefit from our discussion because it includes actionable tools suggested for managing stress, bolstering the gut microbiome, and immunity—all of which stand to improve overall health, vitality and longevity in males and females.

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Dr. Sara Gottfried
Website: https://www.saragottfriedmd.com
Academic Profile: https://bit.ly/3wI7vBz
Medical Practice: https://bit.ly/3jcopoE
Twitter: https://twitter.com/drgottfried
Instagram: https://www.instagram.com/saragottfriedmd
TikTok: https://www.tiktok.com/@saragottfriedmd
YouTube https://www.youtube.com/drgottfried
Facebook https://www.facebook.com/DrGottfried
LinkedIn: https://www.linkedin.com/in/drgottfried
The Critical Link Between Healthy Hormones and Your Relationships: https://bit.ly/40aKXqx

Articles
Women: Diet, Cardiometabolic Health, and Functional Medicine: https://bit.ly/3WPsjl0
Continuous glucose monitoring metrics for earlier identification of pre-diabetes: protocol for a systematic review and meta-analysis: https://bit.ly/3HDX9cc
Brief structured respiration practices enhance mood and reduce physiological arousal: https://bit.ly/3wEvGRf

Books
The Hormone Cure: https://amzn.to/3XMofU7
Women Food and Hormones: https://amzn.to/3Hfvywp

Other Resources
Genova Diagnostics Metabolomix Test: https://bit.ly/3HDfPc3
Genova Diagnostics NutrEval: https://bit.ly/3JlHmQB
SpectraCell Laboratories Micronutrient Test: https://bit.ly/3WMJmnS
Omega Quant Tests: https://bit.ly/3kUiiFT
Cleveland HeartLab® Cardiometabolic Disease: https://bit.ly/3Jl4jTX
Genova Diagnostics Stool Test: https://bit.ly/3JqaVR8
Thorne Gut Health Test: https://thor.ne/y9GEp
"Men are not the patriarchy," Pat McCabe: https://bit.ly/3HFU3nW

Timestamps
00:00:00 Dr. Sara Gottfried
00:03:51 ROKA, Thesis, LMNT, Momentous
00:07:50 Women, Family History, Heredity & Environment
00:11:00 Puberty, Stress, Menstrual Cycles, Intrauterine Devices (IUDs)
00:17:26 Tool: Sex Hormones, Microbiome, Estrobolome & Disease; Biomarker Testing
00:25:11 Nutritional Testing; Vegetables, Microbiome & Disease
00:31:13 AG1 (Athletic Greens)
00:32:22 Microbiome, Prebiotics & Probiotics, Inflammation
00:36:08 Microbiome Testing, Magnesium, Constipation & Thyroid
00:42:25 Female Colonoscopy; Network Effect & Modern Medicine, Stress Factors
00:45:13 Constipation, Stress & Trauma, Autonomic Balance
00:55:35 Constipation Relief, Stress, Breathwork & Meditation
01:02:58 Systemic & Societal Stress Unique to Females
01:08:19 InsideTracker
01:09:23 Testing & Future Behavior
01:11:55 Polycystic Ovary Syndrome (PCOS) & Cardiometabolic Disease; Stress
01:22:57 PCOS, Insulin, Glucose Monitoring and Management; Data Access
01:29:48 Behaviors for Vitality; Exercise & Body Phenotype; Cortisol
01:36:40 Cortisol Supplements: Ashwagandha, Rhodiola, Fish Oil, Phosphatidylserine
01:42:36 Cortisol, Anxiety & Immune System; Adrenal Function, Resilience
01:48:07 Tool: Omega-3 Fatty Acids, Inflammation, Specialized Pro-Resolving Mediators
01:54:20 Oral Contraceptives, Benefits & Risks; Ovarian Cancer; Testosterone
02:06:50 Fertility, Follicular & Anti-Mullerian Hormone (AMH) Assessments
02:10:29 Menopause & Hormone Replacement Therapy; Women’s Health Initiative
02:15:30 Perimenopause, Cerebral Hypometabolism, Metabolism & Estrogen
02:21:49 Intermittent Fasting, Ketogenic Diet, Metabolic Flexibility
02:23:29 Stool Testing
02:25:32 Coronary Artery Calcium (CAC) Test, ACE Score & Disease
02:31:56 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Neural Network Newsletter, Momentous

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