Addison's disease: causes, signs, diagnosis and treatment

#Addison's disease, also known as #adrenal insufficiency, is a rare #disorder that occurs when your body doesn't produce enough of certain hormones. In Addison's disease, your adrenal glands, located just above the kidneys, produce too little cortisol and often too little aldosterone.
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Key points:
0:00 | Def- Addison's disease
0:40 | causes of Addison's disease
1:50 | signs and symptoms
2:55 | diagnosis of Addison's disease
4:37 | treatment of Addison's disease
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Problematic adrenal glands themselves are the cause of most cases of Addison's disease (or primary adrenal insufficiency). 70% of Addison's disease is caused by autoimmune diseases. It occurs when the body's immune system accidentally targets the adrenal glands. The outer layer of the glands is destroyed by an autoimmune attack.
The adrenal glands can be damaged by persistent infections, including tuberculosis, HIV, and various fungi. Addison's disease can also be caused by cancer cells traveling to the adrenal glands from other areas of the body. Although rare, bacterial infections can damage the adrenal glands.
The most definitive way to diagnose Addison’s is to measure hormone levels in the blood before and after giving ACTH.
Diagnosis of patient with Addison's disease In a hospital or clinic, is frequently done by routine blood tests. Additionally, as a symptom of chronic Addison's disease, we need to look for hyperpigmentation, or darkening, of the skin or gums.
once its suspected, blood test including, complete blood count, serum electrolytes, renal function tests and absolute eosinophil count should be obtained.