1. GENERAL TOXICOLOGY HISTORY OF TOXICOLOGY JOSEPH ORFILA FORENSIC TOXICOLOGY CLINICAL TOXICOLOGY

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TOXICOLOGY

A STUDY OF EFFECTS OF POISONS ON LIVING ORGANISMS
FORENSIC toxicology deals with medico-legal aspects of toxic effects of drugs and chemicals in man.
Introduction To Toxicology
Evolution of Toxicology
Principals of Toxicology

TOXICOLOGY
Toxicum = Poison (Latin)
Toxicom = Arrow Poison (Greek)
Logia = Science or Study

TOXICOLOGY
“Toxicology is the study of poison on living organism”
“Toxicology is that branch of medical science which deal with poisons with reference to not only their origin and properties but also the symptoms which they produce.
It also includes the lethal dose and its fatal results and various remedies and measures to combat their effects.”

HISTORY
Mathieu Joseph Bonaventure Orfila (1787-1853)
Was a Spanish Toxicologist and Chemist
Often called the “Father of Toxicology” was the first great 19th century exponent of Forensic Medicine.
He was the founder of the Science of Toxicology.
He put the base of “Forensic Toxicology”
Orfila worked to make Chemical Analysis a routine part of forensic medicine and made studies of Asphyxiation, the Decomposition of Bones and Exhumation.
Orfila discovered detecting arsenic in solutions if not in the human body.
.He published the first scientific treatise on the detection of poisons and their effects on animals.
This was the work that established “Forensic Toxicology” as a legitimate science endeavor.
He wrote first book in 1815
.He stressed legal implications
.He devised analytical procedures
.This book was basis for all future experimental and forensic toxicological evolutions.
Botany, Zoology, Biology, Chemistry, Pharmacology, Physiology, Bio-Chemistry, Genetics

TOXICOLOGY
1. Environmental toxicology
2. Occupational Toxicology
3. Clinical Toxicology
4. Veterinary Toxicology
5. Forensic toxicology

Forensic toxicology
is a discipline which combines analytical chemistry with toxicological principals
in order to deal with the medico-legal aspects of the toxic effects of drugs and chemicals on man.

A STUDY OF EFFECTS OF POISONS ON LIVING ORGANISMS

FORENSIC toxicology also deals with medico-legal aspects of toxic effects of drugs and chemicals in man.

CLINICAL toxicology involves with specific diseases caused by the toxic substances and their treatment.

POISON / TOXIC substance is
any chemical that is capable of
producing a detrimental effect
on a living organism.